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TG Therapeutics, Inc.
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NASDAQ: TGTX Healthcare Pharma 🔎 Screen
🏹 Trader: 🎯 Near 52W High | BRS 74 Forming View all →
$7.7B
Market Cap
10.8
P/E
0.14
PEG
26.6%
ROCE
102.8%
ROE
0.39
D/E
20.0%
OPM
-6.2%
% from 52W High
87
α RS
🔍 TGTX is showing a multi-screen setup because it matches 19 of 39 tracked screener presets, RS Rating is 87, an ECS of 88.3 last quarter, and it has maintained a 21-day Near 52-Week High momentum persistence. Net: Broad signal stack, not a recommendation. ? Conviction RS Rating ECS Momentum Streaks
Sources
Conviction 19/39 · RS Rating 87 · ECS 88.3 · Near 52-Week High streak: 21d
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🌏 Global Investor Returns
Currency-adjusted total returns for TGTX including FX impact
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📈 Price History
Ratio Health
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About

TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. The company provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company’s development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton’s tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; and Jiangsu Hengrui Medicine Co. The company was incorporated in 1993 and is based in Morrisville, North Carolina.

Key Ratios Snapshot
📈 Growth Pattern
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⭐ Superinvestors Holding TGTX
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Manager Shares Value % of Fund Period
Jim Simons Renaissance Technologies LLC 340.9K $11.3M 0.02% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

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📊 MIXED TG Therapeutics Q1 2026: U.S. BRIUMVI revenue $195M, raised full-year guidance to $885-900M.
Revenue & Profitability
Q1 2026 U.S. BRIUMVI net product revenue was approximately $195 million, up 63% year-over-year. Total revenue was $205 million. Operating income was $34.8 million versus $8.6 million in Q1 2025. Net income was $19.8 million, or $0.12 per diluted share, compared to $5.1 million, or $0.03 per diluted share a year ago. The company raised full-year 2026 global revenue guidance to approximately $925 million.
Outlook
Management believes the company is still early in the BRIUMVI adoption curve and sees long-term opportunity well above consensus peak estimates. They view the MS market as large and potentially expandable with subcutaneous offerings. Competitors include established products from large organizations, but management expects BTK inhibitors like remibrutinib to not materially impact the CD20 class.
Growth Drivers
Key growth levers include record new patient enrollments in Q1, better-than-expected persistence, and expansion of the IV franchise. The ENHANCE study (simplified dosing) and subcutaneous BRIUMVI (expected launch 2028) could nearly double addressable market. Pipeline expansion into myasthenia gravis and treatment-resistant schizophrenia, plus azer-cel in progressive MS, offer additional growth.
Balance Sheet & CapEx
Not discussed explicitly as CapEx. However, the company expects approximately $100 million in expenses for subcutaneous manufacturing and secondary manufacturer startup, which are expensed through R&D. They extended their Blue Owl facility to enhance financial flexibility and repurchased $100 million of stock in Q1.
Margins
Revenue growth is outpacing expense growth. For 2026, full-year operating costs excluding stock-based comp are guided to approximately $350 million, plus $100 million for subcutaneous manufacturing. Gross-to-net is expected to average around 65% for the year. Operating income improved to $34.8 million from $8.6 million year-over-year.
Key Risks
Risks mentioned include forward-looking statements regarding operational and financial performance, clinical trial outcomes, regulatory approvals, and competitive dynamics. In Q&A, the potential impact of BTK inhibitor approvals was discussed, but management downplayed the risk. No other specific risks were flagged.
Generated by AI · Q1 2026 results · Not investment advice
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✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
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📞 Earnings Call Transcripts (5)
Q2 2026 Q2 2026 2026-08-03
Q2 saw record BRIUMVI growth, with U.S. net revenue up 64% year-over-year and guidance raised to $890M-$905M. Pipeline advances included positive ENHANCE phase III data and progress on subcutaneous BRIUMVI, with expansion into new indications and strong cash reserves supporting future growth.
Q1 2026 Q1 2026 2026-05-06
Q1 2026 saw record revenue and patient growth, with U.S. BRIUMVI net revenue up 63% year-over-year and global revenue surpassing $200 million. Full-year guidance was raised, pipeline programs advanced, and $100 million in shares were repurchased.
Q4 2025 Q4 2025 2026-02-26
Delivered $616M global revenue in 2025, driven by 92% year-over-year BRIUMVI growth and strong Q4. Reaffirmed 2026 guidance of $825–$850M U.S. net revenue, with continued share gains, robust pipeline progress, and expanded commercial initiatives.
Q3 2025 Q3 2025 2025-11-03
Q3 saw record BRIUMVI sales, 93% revenue growth year-over-year, and raised 2025 guidance to $585M. Profitability continued for a sixth quarter, with strong patient retention, expanding field force, and pipeline progress supporting long-term growth.
Q2 2025 Q2 2025 2025-08-04
Q2 2025 saw 91% year-over-year revenue growth, driven by BRIUMVI's expanding market share and strong patient persistence. Full-year revenue guidance was raised to $570–$575 million, with continued investment in SubQ and IV enhancements and a robust cash position of $279 million.
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Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

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Investment Risk:
Investing in securities, including US equities and ETFs, involves inherent risks including the potential loss of principal. All investments are subject to market fluctuations, economic conditions, regulatory changes, and other factors that may affect their value. Past performance is not indicative of future results. This analysis is provided for informational and educational purposes only and should not be construed as investment advice under any circumstances.

No Investment Recommendation:
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Conflict of Interest Disclosure:
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Information Sources:
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