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Precigen, Inc.
NASDAQ: PGEN Healthcare Pharma 🔎 Screen
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$2.3B
Market Cap
10.9
P/E
0.38
PEG
-256.0%
ROCE
N/M
ROE
4.65
D/E
-1,141.1%
OPM
-0.3%
% from 52W High
93
α RS
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🌏 Global Investor Returns
Currency-adjusted total returns for PGEN including FX impact
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📈 Price History
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About

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases.

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📈 Growth Pattern
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Manager Shares Value % of Fund Period
Steve Cohen Point72 Asset Management 6.64M $25.7M 0.03% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

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📊 MIXED Precigen's PAPZIMEOS generated $21.6M in Q1 2026, first full quarter of launch.
Revenue & Profitability
Q1 2026 total revenue was $23.3 million, including $21.6 million from PAPZIMEOS sales (up from $3.4 million in Q4 2025). Operating loss was $6.0 million, net loss was $7.9 million ($0.02 per share). Cash, equivalents, and investments totaled $56.7 million at quarter end. Cash used in operations was $43.8 million, including $13 million in non-recurring outflows; management expects significantly lower cash use in Q2 and cash flow breakeven by end of 2026.
Outlook
Management reported accelerating revenue momentum into Q2 2026, driven by strong provider adoption at both academic centers and community practices. They expect continued demand growth supported by the permanent J-code (effective April 1) and extensive payer coverage. No macroeconomic headwinds were discussed; the company reiterated that its cash and receivables will fund operations through cash flow breakeven by the end of 2026.
Growth Drivers
Key growth levers include the accelerating launch of PAPZIMEOS, with approximately 400 patients registered in the patient hub (25% from community practices) and robust quarter-over-quarter revenue growth from $3.4M to $21.6M. The permanent J-code simplifies claims processing. Additionally, the pipeline candidate PRGN-2009 is advancing in Phase II trials for head and neck and cervical cancers, with data expected in the second half of 2026.
Balance Sheet & CapEx
Not discussed in this earnings call.
Margins
Management did not explicitly discuss gross margins. Operating loss for Q1 2026 was $6.0 million on $23.3 million revenue. R&D costs decreased year-over-year due to prior expensing of manufacturing costs, but are expected to increase later in 2026. SG&A rose $8.7 million due to commercial activities. The company expects cash flow breakeven by end of 2026, implying improving operating leverage.
Key Risks
Management reminded listeners of forward-looking statements and risks detailed in SEC filings. No specific risks were highlighted on the call. Analysts asked about hub conversion rates and modeling considerations, which management declined to detail until further quarters.
Generated by AI · Q1 2026 results · Not investment advice
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✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
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📞 Earnings Call Transcripts (5)
Q2 2026 Q2 2026 2026-08-04
Q2 2026 saw PAPZIMEOS revenue surge over 145% sequentially to $53.1 million, driving profitability and broad adoption as the new RRP standard of care. Gross margin reached 95%, with strong payer coverage and continued growth expected as the launch matures.
Q1 2026 Q1 2026 2026-05-13
PAPZIMEOS achieved $21.6M in Q1 2026 revenue, marking rapid adoption as the new RRP standard of care, with broad payer coverage and strong physician enthusiasm. Cash position is solid, with operations funded through 2026 and continued expansion expected.
Q4 2025 Q4 2025 2026-03-25
PAPZIMEOS launch drove a 149% revenue increase in 2025, with Q1 2026 revenue expected to exceed $18 million. Broad payer coverage, strong physician uptake, and a permanent J-code are accelerating adoption, while European expansion and pediatric trials are underway.
Q3 2025 Q3 2025 2025-11-13
PAPZIMEOS secured full FDA approval and launched as the first therapy for adult RRP, showing strong efficacy, safety, and rapid commercial uptake. Q3 ended with $123.6M in cash, and breakeven is targeted by end of 2026, supported by robust demand and payer coverage.
Q4 2024 Q4 2024 2025-03-19
PRGN-2012 advanced rapidly to FDA priority review, with pivotal data showing 51% durable complete response in RRP. Financially, a $126.2M net loss was offset by new funding, supporting operations into 2026 as commercialization preparations accelerate.
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📊 Analysis Methodology

This comprehensive investment analysis was conducted using The Finmagine™ Stock Analysis & Ranking Methodology, a proprietary framework that systematically evaluates stocks across five critical dimensions: Financial Health, Growth Prospects, Competitive Positioning, Management Quality, and Valuation.

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Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

⚠️ Important Disclaimers — Please read without fail.

Investment Risk:
Investing in securities, including US equities and ETFs, involves inherent risks including the potential loss of principal. All investments are subject to market fluctuations, economic conditions, regulatory changes, and other factors that may affect their value. Past performance is not indicative of future results. This analysis is provided for informational and educational purposes only and should not be construed as investment advice under any circumstances.

No Investment Recommendation:
This analysis does not constitute, nor should it be interpreted as, an offer, solicitation, or recommendation to buy, sell, or hold any securities or financial products. Investors are strongly advised to conduct their own independent research and due diligence and to consult with a licensed financial advisor or an SEC-registered investment adviser before making any investment decisions, taking into account their individual financial situation, risk tolerance, and investment objectives.

Not SEC-Registered:
Finmagine is not registered as an investment adviser with the U.S. Securities and Exchange Commission (SEC) or any state securities authority. Nothing on this platform constitutes investment advice as defined under the Investment Advisers Act of 1940.

Conflict of Interest Disclosure:
The author and/or analyst may currently hold or have previously held positions in the securities discussed. Any such positions are not intended to influence the objectivity or independence of the analysis. This research is produced independently and is not sponsored, endorsed, or commissioned by any company or institution.

Information Sources:
The analysis is based on publicly available information including SEC filings (10-K, 10-Q), annual reports, management commentary, and publicly available financial data. Information is believed to be accurate as of the date of publication but may be subject to change without notice. Readers are encouraged to independently verify all information before acting upon it.

Forward-Looking Statements:
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