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Guardant Health, Inc.
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$21.3B
Market Cap
P/E
PEG
-29.3%
ROCE
348.4%
ROE
-16.94
D/E
-44.5%
OPM
-3.4%
% from 52W High
94
α RS
🔍 GH is showing a high-conviction setup because it matches 7 of 37 tracked screener presets, Sector RRG has Health Care in the Leading quadrant with the trail still strengthening, and RS Rating is 94 (top decile vs market). Net: Broad signal stack, not a recommendation. ? Conviction RRG RS Rating
Sources
Conviction 7/37 · Health Care in Leading quadrant · RS Rating 94
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🌏 Global Investor Returns
Currency-adjusted total returns for GH including FX impact
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📈 Price History
Ratio Health
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By Category
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About

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally.

Key Ratios Snapshot
📈 Growth Pattern
📊 Quick Scorecard
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⭐ Superinvestors Holding GH
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Manager Shares Value % of Fund Period
Steve Cohen Point72 Asset Management 695.9K $64.3M 0.08% Mar 2026
Cathie Wood ARK Investment Management 486.7K $45.0M 0.35% Mar 2026
Jim Simons Renaissance Technologies LLC 337.6K $31.2M 0.05% Mar 2026
Steve Cohen Point72 Asset Management 10.50M $17.7M 0.02% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

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📊 MIXED Guardant Health Q1 2026 revenue $302M (+48% YoY); Shield volumes 44k tests.
Revenue & Profitability
Q1 2026 total revenue was $302 million, up 48% year-over-year. Oncology revenue grew 36% to $205 million, biopharma revenue grew 17% to $53 million, and screening revenue grew from $6 million to $42 million. Non-GAAP gross margin was 66% (vs. 65% a year ago). Adjusted EBITDA loss was $59 million, and free cash flow burn was $71 million. The company ended the quarter with $1.2 billion in cash and investments.
Outlook
Management's view is that the demand environment is strong across all segments. They raised full-year 2026 revenue guidance to $1.30-$1.32 billion (32-34% growth) and expect Shield volume of 230,000-245,000 tests. The company aims for company-wide cash flow breakeven by the end of 2027. Positive early signals from the Quest partnership and DTC campaigns are noted.
Growth Drivers
Key growth drivers include oncology volume growth of 47% (Guardant360 Liquid 30%, Reveal >100%), Shield volume growth driven by DTC campaigns, the Quest Diagnostics partnership, and EMR integration. Biopharma growth is supported by new CDx partnerships (Merck, Nuvalent) and InfinityAI-driven insights. Expansion of Shield multi-cancer detection in Asia via Manulife is an additional lever.
Balance Sheet & CapEx
Not discussed in detail in this earnings call. The company is investing in sales force expansion (oncology and screening) and marketing campaigns. Free cash flow burn is expected to be $185-$195 million for full-year 2026, a year-over-year improvement.
Margins
Non-GAAP gross margin was 66% in Q1 2026, up from 65% a year ago. Shield gross margin improved from 18% to 56% driven by higher ASP and lower cost per test ($420 from $520). Guardant360 Liquid cost per test decreased by nearly $200 due to the NovaSeq X transition. Full-year 2026 gross margin guidance is 64%-65%. Shield cost per test is expected to decline to ~$200 at scale.
Key Risks
Key risks flagged include the timing and outcome of FDA approval for Guardant360 Liquid, the camizestrant AdCom vote (6-3 against), which may delay or limit therapy monitoring use. MolDX reimbursement decisions for Reveal are pending. Shield commercial coverage for patients under 65 is not yet established. ACS guideline inclusion timing is uncertain. Weather impact in Q1 was as expected.
Generated by AI · Q1 2026 results · Not investment advice
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✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
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📞 Earnings Call Transcripts (5)
Q2 2026 Q2 2026 2026-07-30
Q2 2026 saw 44% revenue growth to $335M, driven by strong oncology, biopharma, and screening performance. Major milestones included FDA approvals, Shield's inclusion in ACS guidelines, and UnitedHealth coverage, expanding access to 70M lives. Full-year guidance was raised on robust demand and operational efficiency.
Q1 2026 Q1 2026 2026-05-07
Q1 2026 saw 48% revenue growth to $302M, driven by strong oncology, biopharma, and screening performance. Raised full-year guidance to $1.30–$1.32B, with Shield and Guardant360 products leading growth and continued investment in commercial expansion.
Q4 2025 Q4 2025 2026-02-19
Delivered 39% Q4 and 33% full-year revenue growth in 2025, driven by innovation and adoption in oncology and screening. 2026 guidance projects 27%–30% revenue growth, with Shield and Reveal as key drivers. Free cash flow burn improved, and core business is now cash flow positive.
Q3 2025 Q3 2025 2025-10-29
Q3 2025 saw 39% revenue growth and record annualized revenue, with strong performance across oncology, biopharma, and screening. Shield and Reveal volumes accelerated, gross margins improved, and guidance for 2025 was raised. Cash flow breakeven is targeted by 2027.
Q2 2025 Q2 2025 2025-07-30
Q2 2025 revenue rose 31% year-over-year to $232M, with strong growth in Oncology, Biopharma, and Screening. Guidance for 2025 was raised across all segments, driven by volume growth, improved margins, and expanded guideline inclusion for Shield.
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📊 Analysis Methodology

This comprehensive investment analysis was conducted using The Finmagine™ Stock Analysis & Ranking Methodology, a proprietary framework that systematically evaluates stocks across five critical dimensions: Financial Health, Growth Prospects, Competitive Positioning, Management Quality, and Valuation.

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Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

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Investment Risk:
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No Investment Recommendation:
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Information Sources:
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