Loading…
Amylyx Pharmaceuticals
NASDAQ: AMLX Healthcare Pharma 🔎 Screen
🏹 Trader: ⭐ All Three 🚀 Stage 2 + Near High 📈 Stage 2 🎯 Near 52W High 📊 High Volume | BRS 93 Elite View all →
📈 Stage 2 detected Find the fundamental catalyst → → run Growth Triggers in Ask AI
$3.7B
Market Cap
21.0
P/E
PEG
-1,922.4%
ROCE
-61.6%
ROE
0.02
D/E
OPM
-6.5%
% from 52W High
98
α RS
🔍 AMLX is showing a high-conviction setup because it matches 6 of 37 tracked screener presets, Sector RRG has Health Care in the Leading quadrant with the trail still rolling over, and RS Rating is 98 (top decile vs market). Net: Broad signal stack, not a recommendation. ? Conviction RRG RS Rating
Sources
Conviction 6/37 · Health Care in Leading quadrant · RS Rating 98
⚖️ Compare 🔒 Generate Report 🔒 Research Packet 📚 Guides
🌏 Global Investor Returns
Currency-adjusted total returns for AMLX including FX impact
🌏
Click 🌏 Returns tab to load data
📈 Price History
Ratio Health
Excellent
Good
Average
Poor
By Category
📊 Sector Averages
About

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States.

Key Ratios Snapshot
📈 Growth Pattern
📊 Quick Scorecard
Loading…
⭐ Superinvestors Holding AMLX
View All Superinvestors →
Manager Shares Value % of Fund Period
Steve Cohen Point72 Asset Management 106.5K $1.5M 0.00% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

🔒
Premium Feature
AI-generated 10-section company profile — business model, financials, strengths, risks & management quality
Upgrade to Premium
Already a member? Log in
📐
3-Statement Financial Model
Bear / Base / Bull projections · DCF fair value · Reverse-DCF
Open Model →
📊 MIXED Phase 3 LUCIDITY trial fully enrolled; top-line data expected Q3 2026.
Revenue & Profitability
Total operating expenses in Q1 2026 were $43.8 million, up 16% year-over-year. Research and development expenses were $27.6 million, driven by avexitide clinical development and a $4 million milestone payment. Selling, general, and administrative expenses were $16.2 million, increased due to commercial preparation costs. The company ended the quarter with $279.8 million in cash and marketable securities, providing runway into 2028.
Outlook
Management highlighted the profound unmet need in PBH, with an estimated 160,000 patients in the U.S. following bariatric surgery and no FDA-approved therapies. The upcoming ICD-10 code for PBH, effective October 2026, signals growing medical community recognition. The company is optimistic about avexitide's potential to become the first approved treatment.
Growth Drivers
The primary growth driver is the potential approval and commercial launch of avexitide for PBH, targeted for 2027. Pipeline progress includes AMX0114 for ALS with biomarker data expected in June 2026, AMX0035 for Wolfram syndrome with longer-term data upcoming, and AMX0318, a long-acting GLP-1 antagonist, with IND-enabling studies underway.
Balance Sheet & CapEx
Not discussed in this earnings call.
Margins
Not discussed in this earnings call. As a pre-revenue company, margin discussion is not applicable.
Key Risks
Key risks include potential negative results from the LUCIDITY trial, variability in hypoglycemic events, and the possibility of a placebo effect. Commercial execution risks include scaling sales and medical teams, market access, and competition. Regulatory risks include the need for FDA approval and the timing of NDA submission.
Generated by AI · Q1 2026 results · Not investment advice
🔒
Free Account Required

Create a free Finmagine account to access Finmagine™ Scorecard.

See how this company scores across 5 dimensions — Financial Health, Growth Prospects, Competitive Position, Management Quality, and Valuation — powered by 30+ computed ratios.

Create Free AccountLog In
🔒
Premium Feature

Upgrade to Finmagine Premium to unlock Ask AI.

Get 25 expert AI analysis templates — Business KPIs, Comprehensive, Forensic Governance, Peer Comparison, Risk-Reward, Full Research Report, IPO Decoder, Red Flag Detector, and more — ready to paste into ChatGPT, Claude, Gemini, or Perplexity.

Upgrade to PremiumCreate Free Account
🔒
Premium Feature

Upgrade to Finmagine Premium to unlock Peer Comparison.

Compare this company side-by-side against its sector peers with financial metrics, ratio benchmarking, and relative performance across all key dimensions.

Upgrade to PremiumCreate Free Account
✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
🔍
🔎 See cross-company document search → ?
📞 Earnings Call Transcripts (5)
Q2 2026 Q2 2026 2026-08-06
Phase III LUCIDITY trial for avexitide in PBH nears top-line data, with NDA and commercial launch preparations underway for 2027. Q2 2026 ended with $250.8M in cash, supporting a runway into 2028, while pipeline programs and disease awareness efforts advance.
Q1 2026 Q1 2026 2026-05-07
Advanced pivotal LUCIDITY trial for avexitide in PBH, with top-line data expected next quarter and NDA preparations underway. Q1 operating expenses rose 16% year-over-year, with a strong cash position supporting a potential 2027 launch. Expanded access and commercial readiness efforts are progressing.
Q4 2025 Q4 2025 2026-03-03
Advanced pipeline and completed LUCIDITY Phase III trial recruitment for Avexitide, with top-line data expected Q3 2026 and a strong cash position extending runway into 2028. Commercial launch preparations and expanded pipeline efforts continue amid significant unmet need in PBH.
Q3 2025 Q3 2025 2025-11-06
Avexitide's phase III Lucidity trial for PBH is progressing with steady enrollment, now targeting Q1 2026 for recruitment completion and Q3 2026 for top-line data. Financials are strong with $344M in cash, supporting a planned 2027 launch and ongoing pipeline development.
Q2 2025 Q2 2025 2025-08-07
Clinical programs advanced for Avexitide, AMX0035, and AMX0114, with pivotal trials underway and key data readouts expected in 2025-2026. Q2 cash position was $180.8M, operating expenses fell 43% year-over-year, and cash runway extends through 2026.
🔒
Premium Feature

Upgrade to Finmagine Premium to unlock Catalyst Timeline.

Every result, order win, insider trade, ECS update, earnings-call, and SEC announcement for this company — in one chronological lane.

Upgrade to PremiumCreate Free Account
🔒
Premium Feature

Upgrade to Finmagine Premium to unlock Full Report.

Read the complete Finmagine™ investment research report — comprehensive fundamental analysis, business model assessment, competitive positioning, and investment recommendation.

Upgrade to PremiumCreate Free Account

📊 Analysis Methodology

This comprehensive investment analysis was conducted using The Finmagine™ Stock Analysis & Ranking Methodology, a proprietary framework that systematically evaluates stocks across five critical dimensions: Financial Health, Growth Prospects, Competitive Positioning, Management Quality, and Valuation.

🎯
Discover Our Proven Investment Framework Learn how we analyze and rank stocks using advanced quantitative models, multi-dimensional scoring systems, and dynamic discriminatory ranking techniques that have guided successful investment decisions across market cycles.
📊 Explore The Finmagine™ Methodology

A comprehensive, bias-free framework for analyzing and ranking stocks by Financial Strength, Growth Potential, Competitive Edge, Management Quality, and Value.

Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

⚠️ Important Disclaimers — Please read without fail.

Investment Risk:
Investing in securities, including US equities and ETFs, involves inherent risks including the potential loss of principal. All investments are subject to market fluctuations, economic conditions, regulatory changes, and other factors that may affect their value. Past performance is not indicative of future results. This analysis is provided for informational and educational purposes only and should not be construed as investment advice under any circumstances.

No Investment Recommendation:
This analysis does not constitute, nor should it be interpreted as, an offer, solicitation, or recommendation to buy, sell, or hold any securities or financial products. Investors are strongly advised to conduct their own independent research and due diligence and to consult with a licensed financial advisor or an SEC-registered investment adviser before making any investment decisions, taking into account their individual financial situation, risk tolerance, and investment objectives.

Not SEC-Registered:
Finmagine is not registered as an investment adviser with the U.S. Securities and Exchange Commission (SEC) or any state securities authority. Nothing on this platform constitutes investment advice as defined under the Investment Advisers Act of 1940.

Conflict of Interest Disclosure:
The author and/or analyst may currently hold or have previously held positions in the securities discussed. Any such positions are not intended to influence the objectivity or independence of the analysis. This research is produced independently and is not sponsored, endorsed, or commissioned by any company or institution.

Information Sources:
The analysis is based on publicly available information including SEC filings (10-K, 10-Q), annual reports, management commentary, and publicly available financial data. Information is believed to be accurate as of the date of publication but may be subject to change without notice. Readers are encouraged to independently verify all information before acting upon it.

Forward-Looking Statements:
This analysis may contain forward-looking statements, forecasts, or projections that are inherently subject to risks, uncertainties, and assumptions. Actual results may differ materially from those expressed or implied. Finmagine does not undertake any obligation to update such statements in the future.

Limitation of Liability:
The content is provided "as is" without any warranties, express or implied. Finmagine expressly disclaims any liability for errors, omissions, or any losses incurred as a result of reliance on the information provided. Readers assume full responsibility for their investment decisions.