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Adaptive Biotechnologies
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$4.0B
Market Cap
P/E
PEG
-77.9%
ROCE
-27.8%
ROE
0.31
D/E
-20.6%
OPM
0.0%
% from 52W High
96
α RS
🔍 ADPT is showing a high-conviction setup because it matches 3 of 37 tracked screener presets, Sector RRG has Health Care in the Leading quadrant with the trail still strengthening, and RS Rating is 96 (top decile vs market). Net: Broad signal stack, not a recommendation. ? Conviction RRG RS Rating
Sources
Conviction 3/37 · Health Care in Leading quadrant · RS Rating 96
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🌏 Global Investor Returns
Currency-adjusted total returns for ADPT including FX impact
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📈 Price History
Ratio Health
Excellent
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By Category
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About

Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases.

Key Ratios Snapshot
📈 Growth Pattern
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⭐ Superinvestors Holding ADPT
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Manager Shares Value % of Fund Period
Andreas Halvorsen Viking Global Investors 29.99M $416.3M 1.16% Mar 2026
Cathie Wood ARK Investment Management 2.09M $29.1M 0.23% Mar 2026
Steve Cohen Point72 Asset Management 1.02M $14.2M 0.02% Mar 2026
Jim Simons Renaissance Technologies LLC 239.8K $3.3M 0.01% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

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📊 MIXED Adaptive Biotechnologies: MRD revenue up 53% YoY, raises full-year guidance to $260M-$270M
Revenue & Profitability
Total revenue for Q1 2026 was $70.9 million, up 45% year-over-year. MRD revenue grew 53% to $67.1 million. Sequencing gross margin (excluding milestones) was 70%, up from 62% a year ago. Total operating expenses were $90.1 million, up 10% year-over-year. Net loss was $20 million, which included $2.9 million of interest expense. Adjusted EBITDA was a loss of $2.5 million, with MRD segment adjusted EBITDA of $12.1 million. Cash and cash equivalents were approximately $222 million at quarter end.
Outlook
Management sees strong and sustainable demand in MRD, driven by increasing adoption in clinical practice and drug development. The FDA's new clinical trial model incorporating real-time data submission reinforces the value of MRD endpoints. The company expects to achieve positive adjusted EBITDA and positive free cash flow for the full company by the end of 2026. Full-year MRD revenue guidance was raised to $260-$270 million, implying ~25% year-over-year growth (33% excluding milestones).
Growth Drivers
Key growth levers include: clinical volume growth of 41% year-over-year (with community volumes up 67%); blood-based testing now representing 49% of MRD volume; serial monitoring orders driven by Flatiron EMR integration; and pricing improvement (U.S. ASP up 11% year-over-year to $1,360 per test). Pharma backlog grew 24% year-over-year to $254 million, with 10 new registrational studies signed in Q1. DLBCL volumes grew over 19% sequentially. The company is raising its full-year volume growth target to at least 35%.
Balance Sheet & CapEx
Not explicitly discussed in this earnings call. Management noted continued investment in commercial infrastructure, including EMR integrations, reimbursement, and personnel, but no specific CapEx guidance was provided.
Margins
Sequencing gross margin improved to 70% in Q1 2026 from 62% a year ago, driven by NovaSeq efficiencies and favorable pricing. Management sees a path to a 'North Star' of 75% gross margin, with a linear step-up throughout the year. MRD segment adjusted EBITDA turned positive at $12.1 million versus a loss of $4.1 million in the prior year. Total company adjusted EBITDA loss was $2.5 million. Operating expenses are guided to $350-$360 million for the full year.
Key Risks
Risks flagged include: uncertainty around PAMA reporting (management stated they are not subject to current reporting requirements); timing of Medicare bundle renegotiation to increase tests per episode; potential impact from CMS cost-saving initiatives (e.g., CRUSH); and the lumpy nature of pharma revenue quarter-to-quarter. Competition in DLBCL and the need to maintain rapid growth to stay ahead of emerging competition were also noted.
Generated by AI · Q1 2026 results · Not investment advice
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✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
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📞 Earnings Call Transcripts (5)
Q2 2026 Q2 2026 2026-07-29
Q2 saw robust MRD revenue and volume growth, margin expansion, and a strengthened balance sheet. Guidance was raised for MRD revenue and clinical volume, while the separation of Immune Medicine advanced and capital structure was optimized.
Q1 2026 Q1 2026 2026-05-05
Q1 revenue grew 45% year-over-year, led by 53% MRD growth and record clinical volumes. Sequencing gross margin rose to 70%, and full-year MRD guidance was raised to $260M–$270M. Strong adoption, operational efficiency, and expanding pharma partnerships support continued momentum.
Q4 2025 Q4 2025 2026-02-05
Achieved 55% revenue growth and 68% lower cash burn in 2025, with MRD profitability and strong clonoSEQ test volume growth. 2026 guidance targets 22% MRD revenue growth, over 30% test volume increase, and positive company-wide adjusted EBITDA and free cash flow by year-end.
Q3 2025 Q3 2025 2025-11-05
Q3 saw robust MRD revenue growth, margin expansion, and positive cash flow, driven by clinical adoption, EMR integration, and payer wins. Full-year MRD guidance was raised, with strong volume and ASP momentum, while regulatory and competitive positioning remain favorable.
Q2 2025 Q2 2025 2025-08-05
Q2 saw 36% revenue growth, MRD business profitability, and raised full-year guidance. EMR integrations and updated guidelines are driving volume and pricing gains, with strong momentum in both clinical and pharma MRD segments.
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Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

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Investment Risk:
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Information Sources:
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